Sergio Busquets is expected to be out of action for at least three weeks after sustaining a knee injury on international duty with Spain.
The midfielder came off early during Saturday’s 1-1 Nations League draw with Switzerland and is now set to undergo an MRI scan on Monday.
According to Catalunya Radio, Busquets will miss “a minimum of three weeks” after suffering a mild knee ligament sprain.
Barcelona have a packed fixture list in December and Busquets could be back in time for a run of La Liga games in December after the Champions League group stage has concluded.
Busquets’s injury look like giving Miralem Pjanic a chance to establish himself in the starting XI alongside Frenkie de Jong, although Carles Alena may be hoping for more game time too.