For once there’s nothing really riding on this game but you can bet both teams will still be desperate for victory.
So let’s get straight to it and look at how Barcelona could line up on Sunday.
Ernesto Valverde is probably going to go with his strongest team so the only question in defence is who plays at right-back?
Sergi Roberto missed the Deportivo clash due to suspension but will probably return at the expense of Nelson Semedo.
The rest of the back four picks itself with Gerard Pique, Samuel Umtiti and Jordi Alba starting in front of Marc-Andre ter Stegen.
Expect to see Philippe Coutinho and Andres Iniesta on the flanks and Ivan Rakitic and Sergio Busquets in the middle.
Ousmane Dembele is another option but Valverde basically doesn’t trust him in the big games yet.
Denis Suarez has also been pushing for game time after a couple of impressive little cameos and so he may get a couple of minutes at the end if Barca are 29-0 up.
It’ll be Lionel Messi and Luis Suarez won’t it?
Possible starting X: Ter Stegen; Roberto, Pique, Umtiti, Alba; Coutinho, Rakitic, Busquets, Iniesta; Messi, Suarez.
How do you think Barcelona should line up against Real Madrid? Let us know your thoughts and predictions in the comments below!