Mircea Lucescu’s men have travelled without a host of first-team players, largely due to Covid-19, meaning Barca will be expected to win with some comfort.
This could be a good chance for Ronald Koemant to rotate his squad and offer some players a breather ahead of Saturday’s La Liga clash with Real Betis.
Let’s look at how they might line up:
Marc-Andre ter Stegen is expected to be passed fit ahead of the game after knee surgery and could make his first appearance of the season in goal.
Sergino Dest looks set to come back into the team at right-back, while Junior Firpo could get a rare start on the opposite flank.
Barca have few options in central defence which means Gerard Pique and Clement Lenglet should continue.
Miralem Pjanic is pushing hard for a start in midfield ahead of Sergio Busquets and could get the nod against Dynamo Kiev on Wednesday.
The 30-year-old looks set to partner Frenkie de Jong in midfield, who has dropped into defence in recent games, unless Ronald Koeman decides to rest the Dutchman.
This looks a good time for Koeman to rest Lionel Messi who has played every single minute for club and country so far this season.
The Barca boss has plenty of options if he wants to freshen up his attack and looks certain to bring Pedri back into his starting XI.
Francisco Trincao is another player pushing for a start, while Ansu Fati, Antoine Griezmann and Ousmane Dembele could also get the nod.
Possible XI: Ter Stegen; Dest, Pique, Lenglet, Firpo; Pjanic, De Jong; Dembele, Pedri, Fati; Griezmann.
How do you think Barcelona will line up against Dynamo Kiev? Let us know your thoughts, predictions and teams in the comments below!